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Submitted
August 29, 2023
Accepted
December 20, 2023
Published
December 29, 2023
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Abstract

Background: Herbal plants contain important substances termed phytochemicals. Phytochemicals occur naturally in herbal plants as secondary metabolites with vital properties, such as antibiotics. Recently, there has been a keen focus on herbal plants such as Caylusea abyssinica because of their ability to cure diseases and conditions that are challenging to modern medicine; hence, they are relevant to human health today. This study was conducted to screen the phytochemicals of Caylusea abyssinica and explain their medical significance.


Methods: GC-MS and LC-MS were used to determine the phytochemicals extracted from the root bark of Caylusea abyssinica. Root bark samples were extracted using hexane solvent and analyzed using chromatographic methods.


Results: Using GC-MS/LC-MS and solvent extraction, 16 new phytochemicals were identified. The phytochemicals are Methyl benzoate, imine, benzaldehyde, O-methyloxime, o-xylene-α,α’-dithiol, benzene, (ethenylsulfinyl), ethanone, 1-phenyl-oxime, benzene-ethanamine, N-(1-methyl ethylidene), aziridine, 2,3-dimethyl-1- (phenylmethyl)-, trans, benzyl 2-pyrrolidinecarboxylate, diphenyl(2-pyrrolidinyl) methanol, pyrrolidine-2-carboxylic acid, methylphenylamide, 2-isothyl ocyanatoethyl, N,N’-diphenethylthiourea, methyl-2-isothiocyanato-3-phenylpropionate, ethylbenzene, 4-benzyloxy-phenylacetonitrile and 1,3,5-cycloheptatriene, 7-ethyl. This study demonstrates the medical importance of phytochemicals.


Conclusion: Cyalusea abyssinica is an essential herb that is rich in various medically important phytochemicals.

Keywords

Phytochemicals LC-MS GC-MS Caylusea abyssinica medicinal

Article Details

Author Biographies

Willy Kemboi, University of Eastern Africa, Baraton, Kenya

Willy Kemboi is a lecturer in the Department of Biological  Sciences at the University of Eastern Africa, Baraton. Currently, he is a Ph.D. student at the University of Nairobi, School of Medicine, Department of Medical Microbiology. His research interest focuses on the utilization of phytochemicals in the treatment of pathogenic bacteria.

Marianne Wanjiru Mureithi, University of Nairobi, Kenya

Dr. Marianne Mureithi serves as the Chair of the Department of Medical Microbiology & Immunology at the Faculty of Health Sciences, University of Nairobi, Kenya, and as Team Leader at the Kenya AIDS Vaccine Initiative - Institute of Clinical Research (KAVI-ICR)

Kefa Ogonyo Bosire, University of Nairobi, Kenya

Dr Kefa Ogonyo Bosire is a senior lecturer in the Department of Pharmacology and Pharmacognosy, School of Pharmacy, College of Health Sciences at the University of Nairobi. He is a member of the East African Pharmacovigilance Initiative(EAPI), a 3-year program to improve pharmacovigilance systems in the region by offering short courses.

How to Cite
Kemboi, W., Mureithi, M. . W., & Bosire, K. O. (2023). Phytochemical Screening and Medicinal Importance of Caylusea Abyssinica Root Bark Extracts. Pan-African Journal of Health and Environmental Science, 2(2), 20–27. Retrieved from https://journals.aua.ke/ajhes/article/view/401
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